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第2019-32期 Advanced In Vivo Fluorescence Imaging: Seeing is Believing
发布时间:2019-05-07 查看次数:

报告题目:Advanced In Vivo FluorescenceImaging: Seeing is Believing

:王强斌研究员

中国科学院苏州纳米研究所副所长

国家杰出青年基金获得者

报告时间:20195月13日(星期一)下午3:00

报告地点:化学楼新楼819报告厅

报告内容:Fluorescent imaging in the second near-infrared window (NIR-II, 1.0~1.4 μm) is appealing in in vivo imaging due to minimal autofluorescence and negligible tissue scattering in this region, affording maximal penetration depth for deep tissue imaging with high feature fidelity. Herein, for the first time, we reported a new type of NIR-II QDs-Ag2S QDs and executed a series of in vivo imaging studies by using Ag2S QDs. The results show that, by using Ag2S QDs, the tissue penetration length can reach 1.5 cm, and the spatial and temporal resolution of the in vivo imaging can down to 25 µm and 50 ms, respectively, which are improved several to dozens of times in comparison with those using conventional fluorescence nanoprobes in the visible and the first near-infrared window (650-900 nm), offering in situ, real-time visualization of the biological events in vivo. With the advanced NIR-II fluorescence of Ag2S QDs, high signal to noise ratio imaging of tumor growth and angiogenesis, imaging-guided targeting drug-delivery and therapeutics, imaging-guided precision surgery of glioma, and stem cell tracking and regeneration in vivo,etc, have been achieved.

报告人简介:

Passport Picture-QW.JPG王强斌,博士,中科院“百人计划”研究员,博士生导师。2002年于华东理工大学获博士学位,2004-2008年在美国亚利桑那州立大学从事博士后和助理研究教授工作,2008年7月年加入中科院苏州纳米所,任研究员,课题组长,获国家杰出青年基金和万人计划科教领军人才计划支持。现任中国科学院纳米-生物界面重点实验室主任,中国化学会理事,中国化学会纳米化学分会副秘书长,中国生物材料学会影像材料与技术分会副主任委员。研究兴趣包括功能纳米材料、纳米生物技术、近红外II区荧光技术及其转化医学等。主持国家级项目10余项。已发表研究论文105篇。申请专利28项,授权6项。研究成果获2017年江苏省科技进步一等奖。